BIOFOS aims at the development of a portable biosensor system for on‐site quality control against contaminants in milk, olive oil and nut samples. The 6 contaminants that will be targeted as analytesat the 3 selected food categories in BIOFOS are: Aflatoxin M1 and Penicillin (in milk), insecticide (Phosmet) and copper (in olive oil) and Ochratoxin and Aflatoxin B1 (in nuts). Along with the 6 contaminants, BIOFOS will also target at the quantitative detection of lactose, which is a natural ingredient of milk.
BIOFOS’s specific S&T objectives are:
Develop monolithic photonic circuits for label‐free, high‐throughput optical biosensing at 850 nm based on 1:12 MMI couplers and 12‐fold MRR arrays for operation.
Hybrid integration of actives elements (VCSEL and photodiode arrays) on TriPleX boards using flip‐chip bonding and butt‐coupling techniques.
Design and production of aptamers for highly‐selective detection of food contaminants (aflatoxin M1, penicillin antibiotic, phosmet insecticide, copper (Cu+2), ochratoxin and aflatoxin B1).
Development of effective techniques for functionalization of sensor substrates and immobilization of biomediators (aptamers).
Development of robust techniques for regeneration of biomediators (aptamers) and reusability of sensor arrays.
Development of microfluidics for solid and liquid phase treatment.
System integration in a cost‐effective, reusable LoC system and system validation in real settings.